Natural products have been a major source of drugs for centuries. With more than 25% of the pharmaceuticals in use today from natural products. This can be attributed to several factors, including unmet therapeutic needs that drive drug discovery, the remarkable diversity of both chemical structures and biological activities of naturally occuring secondary metabolities and [...]
At an interface between two transparent media of different refractive index (glass and water), light coming from the side of higher refractive index is partly reflected and partly refracted. Above a certain critical angle of incidence, no light is refracted across the interface, and total internal reflection is observed. While incident light is totally reflected [...]
Defining “Ethics” “What is all this, and how does it work?” – the answers to which are sought by science; and “What should we do?” – the answers to which are given by ethics. Ethics is a bridge between science and the deliberate mind. With the word deliberate mind I mean, the mind which seeks [...]
It’s generally understood by the molecular biology research community that the sequencing of the human genome, which will likely take several more years to complete, is relatively trivial compared to definitively characterizing the interactions within the proteome. Non-Static Structure Visualization Unlike a nucleotide sequence, which is a relatively static structure, proteins are dynamic entities that [...]
Cancer is a disease characterized by a shift in the control mechanisms that govern cell survival, proliferation, and differentiation. Cells that have undergone neoplastic transformation usually express cell surface antigens that may be of normal fetal type, may display other signs of apparent immaturity, and may exhibit qualitative or quantitative chromosomal abnormalities, including various translocations [...]